Influence of Isoleucine upon Quinomycin Biosynthesis by Streptomyces sp. 732

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Influence of isoleucine upon quinomycin biosynthesis by Streptomyces sp. 732.

When dl-isoleucine was added to an ammonium nitrate-maltose medium during cultivation of Streptomyces sp. 732, quinomycin B formation was selectively enhanced (from 3 to 70% of the quinomycin mixture) and quinomycin C synthesis was inhibited completely. In addition, two new quinomycins, designated quinomycins D and E, were produced in the presence of isoleucine. These compounds were found to co...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 1967

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.93.4.1327-1331.1967